Group of Prof. Tinnefeld - Faculty for Chemistry and Pharmacy

Figures/Press Releases


G.J. Hedley, T. Schröder, F. Steiner, T. Eder, F. Hofmann, S. Bange, D. Laux, S. Höger, P. Tinnefeld, J.M. Lupton, J. Vogelsang: Picosecond time-resolved photon antibunching measures nanoscale exciton motion and the true number of chromophores, Nat. Commun. 12 (1327).

See Press Release LMU and e-conversion


M. Scheckenbach, T. Schubert, C. Forthmann, V. Glembockyte, P. Tinnefeld: Self-Regeneration and Self-Healing in DNA Origami Nanostructures, Angew.Chem. Int.Ed. 60,4931 – 4938.
Selbstregeneration und Selbstheilung in DNA‐Origami‐Nanostrukturen, Angew. Chem. 2021, 133, 4982 – 4990.

See Press release e-conversion, Fakultät für Chemie und Pharmazie and Chemistry Views

Cover Figure in Angew.Chem. Int.Ed. 2021-60/9 and Angew. Chem. 2021-133/9



K. Trofymchuk, V. Glembockyte, L. Grabenhorst, F. Steiner, C. Vietz, C. Close, M. Pfeiffer, L. Richter, M. L. Schütte, F. Selbach, R. Yaadav, J. Zähringer, Q. Wei, A. Ozcan, B. Lalkens, G.P. Acuna, P. Tinnefeld: Addressable nanoantennas with cleared hotspots for single-molecule detection on a portable smartphone microscope, Nat. Commun. 12(950)

See Press Release LMU


L. Shani, P. Tinnefeld, Y. Fleger, A. Sharoni, B.Y. Shapiro, A. Shaulov, O. Gang, Y. Yeshurun: DNA origami based superconducting nanowires, AIP Advances 11(1)

See Press release Phys.Org.


L.A. Masullo, F. Steiner, J. Zähringer, L.F. Lopez, J. Bohlen, L. Richter, F. Cole, P. Tinnefeld*, F.D. Stefani*: Pulsed-Interleaved MINFLUX, Nano Lett. 21(1), 840–846.

See Press release nanowerk and LMU


K. Kramm, T. Schröder, J. Gouge, A. Vera, K. Gupta, F. Heiss, T. Liedl, C. Engel, I. Berger, A. Vannini , P. Tinnefeld, D. Grohmann*: DNA origami-based single-molecule force spectroscopy unravels the molecular basis of RNA Polymerase III pre-initiation complex stability, Nat. Commun. 11(2828), DOI 10.1038/s41467-020-16702-x

See Press release CeNS

selected by Nat. Commun. in the Editors Highlights section


I. Kaminska, J. Bohlen, S. Rocchetti, F. Selbach, G.P. Acuna, P. Tinnefeld*: Distance dependence of single-molecule energy transfer to graphene measured with DNA origami nano-positioners, Nano Lett. 19, 4257−4262.

See Press release e-conversion and Faculty for Chemistry and Pharmacy
Image used in article from Graphenea


B. Hellenkamp, S. Schmid, O. Doroshenko, O. Opanasyuk, R. Kühnemuth, S. Rezaei Adariani, B. Ambrose, M. Aznauryan, A. Barth, V. Birkedal, M.E. Bowen, H. Chen, T. Cordes, T. Eilert, C. Fijen, C. Gebhardt, M. Götz, G. Gouridis, E. Gratton, T. Ha, P. Hao, C.A. Hanke, A. Hartmann, J. Hendrix, L.L. Hildebrandt, V. Hirschfeld, J. Hohlbein, B. Hua, C.G. Hübner, E. Kallis, A.N. Kapanidis, J.-Y. Kim, G. Krainer, D.C. Lamb, N.K. Lee, E.A. Lemke, B. Levesque, M. Levitus, J.J. McCann, N. Naredi-Rainer, D. Nettels, T. Ngo, R. Qiu, N.C. Robb, C. Röcker, H. Sanabria, M. Schlierf, T. Schröder, B. Schuler, H. Seidel, L. Streit, J. Thurn., P. Tinnefeld, S. Tyagi, N. Vandenberk, A.M. Vera, K.R. Weninger, B. Wünsch, I.S. Yanez-Orozco, J. Michaelis*, C.A.M. Seidel*, T.D. Craggs*, T. Hugel*: Precision and accuracy of single-molecule FRET measurements – a worldwide benchmark study, Nat. Methods 15, 669–676.

see press release LMU Munich


M. Raab, I. Jusuk, J. Molle, E. Buhr, B. Bodermann, D. Bergmann, H. Bosse, P. Tinnefeld:Using DNA origami nanorulers as traceable distance measurement standards and nanoscopic benchmark structures, Sci. Rep. 8(1780).

see press release Excellence Cluster "Nanosystems initiative Munich (NIM)":


P.C. Nickels, B. Wünsch, P. Holzmeister, W. Bae, L.M. Kneer, D. Grohmann, P. Tinnefeld, T. Liedl (2016): Molecular Force Spectroscopy with a DNA Origami Based Nanoscopic Force Clamp, Science 354(6310), 305-307.

CeNS Publication Award 2017


P. Holzmeister, G. P. Acuna, D. Grohmann, P. Tinnefeld (2014): Breaking the Concentration Limit of Optical Single -Molecule Detection, Chem.Soc.Rev. 43(4), 1014-1028

Issue back cover


J.J. Schmied, A. Gietl, Phil Holzmeister, C. Forthmann, C. Steinhauer, T. Dammeyer, P. Tinnefeld (2012): Fluorescence and Super-resolution Standards based on DNA Origami, Nat. Methods 9, 1133–1134.

Press release: German / English


G.P. Acuna, F.M. Möller, P. Holzmeister, S. Beater, B. Lalkens and P. Tinnefeld (2012): Fluorescence Enhancement at Docking Sites of DNA-Directed Self-Assembled Nanoantennas, Science 338(6106), 506-510

Press release, Research Highlight, News & Views


J. Vogelsang, R. Kasper, C. Steinhauer, B. Person, M. Heilemann, M. Sauer, P. Tinnefeld (2008): A reducing and oxidizing system minimizes photobleaching and blinking of fluorescent dyes, Angew. Chem. Int. Ed. 47(29), 5465-5469

including cover picture


J. Roß, P. Buschkamp, D. Fetting, A. Donnermeyer, C.M. Roth, P. Tinnefeld (2007): Multicolor Single-Molecule Spectroscopy with Alternating Laser Excitation for the Investigation of Interactions and Dynamics, J. Phys. Chem. B 111(2), 321-326

including cover picture


D.-P. Herten, A. Biebricher, M. Heilemann, T. Heinlein, C. Müller, P. Schlüter, P. Tinnefeld, K.D. Weston, M. Sauer, J. Wolfrum (2004): Optical single molecule techniques for analytical and biological applications, Rec. Res. Devel. Phys. Chem. 7, 345-368

invited article


P. Tinnefeld, V. Buschmann, K.D. Weston, A. Biebricher, D.-P. Herten, O. Piestert, T. Heinlein, M. Heilemann, M. Sauer (2004): How single-molecule photophysical studies complement ensemble methods for a better understanding of chromophores and interchromophore interactions, Rec. Res. Devel. Phys. Chem. 7, 95-125

invited article