

Publications

Martina Pfeiffer; Kateryna Trofymchuk; Simona Ranallo; Francesco Ricci; Florian Steiner; Fiona Cole; Viktorija Glembockyte; Philip Tinnefeld
Single antibody detection in a DNA origami nanoantenna Journal Article
In: iScience, vol. 24, no. 9, pp. 103072, 2021.
@article{Pfeiffer2021,
title = {Single antibody detection in a DNA origami nanoantenna},
author = {Martina Pfeiffer and Kateryna Trofymchuk and Simona Ranallo and Francesco Ricci and Florian Steiner and Fiona Cole and Viktorija Glembockyte and Philip Tinnefeld},
doi = {10.1016/j.isci.2021.103072},
year = {2021},
date = {2021-09-01},
urldate = {2021-09-01},
journal = {iScience},
volume = {24},
number = {9},
pages = {103072},
publisher = {Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

Viktorija Glembockyte; Lennart Grabenhorst; Kateryna Trofymchuk; Philip Tinnefeld
DNA Origami Nanoantennas for Fluorescence Enhancement Journal Article
In: Acc Chem Res, vol. 54, no. 17, pp. 3338–3348, 2021.
@article{Glembockyte2021,
title = {DNA Origami Nanoantennas for Fluorescence Enhancement},
author = {Viktorija Glembockyte and Lennart Grabenhorst and Kateryna Trofymchuk and Philip Tinnefeld},
doi = {10.1021/acs.accounts.1c00307},
year = {2021},
date = {2021-08-01},
urldate = {2021-08-01},
journal = {Acc Chem Res},
volume = {54},
number = {17},
pages = {3338--3348},
publisher = {American Chemical Society (ACS)},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

Kateryna Trofymchuk; Viktorija Glembockyte; Lennart Grabenhorst; Florian Steiner; Carolin Vietz; Cindy Close; Martina Pfeiffer; Lars Richter; Max L. Schütte; Florian Selbach; Renukka Yaadav; Jonas Zähringer; Qingshan Wei; Aydogan Ozcan; Birka Lalkens; Guillermo P. Acuna; Philip Tinnefeld
Addressable nanoantennas with cleared hotspots for single-molecule detection on a portable smartphone microscope Journal Article
In: Nature Communications, vol. 12, no. 1, 2021.
@article{Trofymchuk2021,
title = {Addressable nanoantennas with cleared hotspots for single-molecule detection on a portable smartphone microscope},
author = {Kateryna Trofymchuk and Viktorija Glembockyte and Lennart Grabenhorst and Florian Steiner and Carolin Vietz and Cindy Close and Martina Pfeiffer and Lars Richter and Max L. Schütte and Florian Selbach and Renukka Yaadav and Jonas Zähringer and Qingshan Wei and Aydogan Ozcan and Birka Lalkens and Guillermo P. Acuna and Philip Tinnefeld},
doi = {10.1038/s41467-021-21238-9},
year = {2021},
date = {2021-02-01},
urldate = {2021-02-01},
journal = {Nature Communications},
volume = {12},
number = {1},
publisher = {Springer Science and Business Media LLC},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

Patrick Eiring; Ryan McLaughlin; Siddharth S Matikonda; Zhongying Han; Lennart Grabenhorst; Dominic A Helmerich; Mara Meub; Gerti Beliu; Michael Luciano; Venu Bandi; Niels Zijlstra; Zhen-Dan Shi; Sergey G Tarasov; Rolf Swenson; Philip Tinnefeld; Viktorija Glembockyte; Thorben Cordes; Markus Sauer; Martin J Schnermann
Targetable Conformationally Restricted Cyanines Enable Photon-Count-Limited Applications* Journal Article
In: Angew Chem Int Ed Engl, vol. 60, no. 51, pp. 26685–26693, 2021, ISSN: 1521-3773.
@article{pmid34606673,
title = {Targetable Conformationally Restricted Cyanines Enable Photon-Count-Limited Applications*},
author = {Patrick Eiring and Ryan McLaughlin and Siddharth S Matikonda and Zhongying Han and Lennart Grabenhorst and Dominic A Helmerich and Mara Meub and Gerti Beliu and Michael Luciano and Venu Bandi and Niels Zijlstra and Zhen-Dan Shi and Sergey G Tarasov and Rolf Swenson and Philip Tinnefeld and Viktorija Glembockyte and Thorben Cordes and Markus Sauer and Martin J Schnermann},
doi = {10.1002/anie.202109749},
issn = {1521-3773},
year = {2021},
date = {2021-01-01},
urldate = {2021-01-01},
journal = {Angew Chem Int Ed Engl},
volume = {60},
number = {51},
pages = {26685--26693},
abstract = {Cyanine dyes are exceptionally useful probes for a range of fluorescence-based applications, but their photon output can be limited by trans-to-cis photoisomerization. We recently demonstrated that appending a ring system to the pentamethine cyanine ring system improves the quantum yield and extends the fluorescence lifetime. Here, we report an optimized synthesis of persulfonated variants that enable efficient labeling of nucleic acids and proteins. We demonstrate that a bifunctional sulfonated tertiary amide significantly improves the optical properties of the resulting bioconjugates. These new conformationally restricted cyanines are compared to the parent cyanine derivatives in a range of contexts. These include their use in the plasmonic hotspot of a DNA-nanoantenna, in single-molecule Förster-resonance energy transfer (FRET) applications, far-red fluorescence-lifetime imaging microscopy (FLIM), and single-molecule localization microscopy (SMLM). These efforts define contexts in which eliminating cyanine isomerization provides meaningful benefits to imaging performance.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

Michael Scheckenbach; Tom Schubert; Carsten Forthmann; Viktorija Glembockyte; Philip Tinnefeld
Self-Regeneration and Self-Healing in DNA Origami Nanostructures Journal Article
In: Angewandte Chemie International Edition, vol. 60, no. 9, pp. 4931–4938, 2021.
@article{Scheckenbach2021,
title = {Self-Regeneration and Self-Healing in DNA Origami Nanostructures},
author = {Michael Scheckenbach and Tom Schubert and Carsten Forthmann and Viktorija Glembockyte and Philip Tinnefeld},
doi = {10.1002/anie.202012986},
year = {2021},
date = {2021-01-01},
urldate = {2021-01-01},
journal = {Angewandte Chemie International Edition},
volume = {60},
number = {9},
pages = {4931--4938},
publisher = {Wiley},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Michael Isselstein; Lei Zhang; Viktorija Glembockyte; Oliver Brix; Gonzalo Cosa; Philip Tinnefeld; Thorben Cordes
Self-Healing Dyes—Keeping the Promise? Journal Article
In: The Journal of Physical Chemistry Letters, vol. 11, no. 11, pp. 4462–4480, 2020.
@article{Isselstein2020,
title = {Self-Healing Dyes—Keeping the Promise?},
author = {Michael Isselstein and Lei Zhang and Viktorija Glembockyte and Oliver Brix and Gonzalo Cosa and Philip Tinnefeld and Thorben Cordes},
doi = {10.1021/acs.jpclett.9b03833},
year = {2020},
date = {2020-05-01},
journal = {The Journal of Physical Chemistry Letters},
volume = {11},
number = {11},
pages = {4462--4480},
publisher = {American Chemical Society (ACS)},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Siddharth S. Matikonda; Gabrielle Hammersley; Nikita Kumari; Lennart Grabenhorst; Viktorija Glembockyte; Philip Tinnefeld; Joseph Ivanic; Marcia Levitus; Martin J. Schnermann
Impact of Cyanine Conformational Restraint in the Near-Infrared Range Journal Article
In: The Journal of Organic Chemistry, vol. 85, no. 9, pp. 5907–5915, 2020.
@article{Matikonda2020,
title = {Impact of Cyanine Conformational Restraint in the Near-Infrared Range},
author = {Siddharth S. Matikonda and Gabrielle Hammersley and Nikita Kumari and Lennart Grabenhorst and Viktorija Glembockyte and Philip Tinnefeld and Joseph Ivanic and Marcia Levitus and Martin J. Schnermann},
doi = {10.1021/acs.joc.0c00236},
year = {2020},
date = {2020-04-01},
journal = {The Journal of Organic Chemistry},
volume = {85},
number = {9},
pages = {5907--5915},
publisher = {American Chemical Society (ACS)},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Lennart Grabenhorst; Kateryna Trofymchuk; Florian Steiner; Viktorija Glembockyte; Philip Tinnefeld
Fluorophore photostability and saturation in the hotspot of DNA origami nanoantennas Journal Article
In: Methods and Applications in Fluorescence, vol. 8, no. 2, pp. 024003, 2020.
@article{Grabenhorst2020,
title = {Fluorophore photostability and saturation in the hotspot of DNA origami nanoantennas},
author = {Lennart Grabenhorst and Kateryna Trofymchuk and Florian Steiner and Viktorija Glembockyte and Philip Tinnefeld},
doi = {10.1088/2050-6120/ab6ac8},
year = {2020},
date = {2020-02-01},
journal = {Methods and Applications in Fluorescence},
volume = {8},
number = {2},
pages = {024003},
publisher = {IOP Publishing},
keywords = {},
pubstate = {published},
tppubtype = {article}
}